Some cats don't like being picked up, and the earlier you get your kitten used to it, the better. A lot of people unknowingly teach their kitten bad habits. They pick up their kitten, she struggles, and they immediately put her down again, thus teaching the kitten that if she objects, she gets her own way.
A better approach is to pick up your kitten and then, if she struggles, continue to hold her gently but firmly. When she settles, lavish lots of praise on her and set her down. Consider a kibble of her favorite kitten food as a reward in moderation.